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Spatial transcriptomics atlas reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment components in colorectal cancer

BACKGROUND: The tumor-promoting role of tumor microenvironment (TME) in colorectal cancer has been widely investigated in cancer biology. Cancer-associated fibroblasts (CAFs), as the main stromal component in TME, play an important role in promoting tumor progression and metastasis. Hence, we explor...

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Detalles Bibliográficos
Autores principales: Peng, Zhiwei, Ye, Manping, Ding, Huiming, Feng, Zhenyou, Hu, Kongwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258101/
https://www.ncbi.nlm.nih.gov/pubmed/35794563
http://dx.doi.org/10.1186/s12967-022-03510-8