SEMA4D/PlexinB1 promotes AML progression via activation of PI3K/Akt signaling

BACKGROUND: Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. SEMA4D is a 150 kDa transmembrane protein that belongs to the IV class of the subfamily of semaphorin family. Previous studies have reported that SEMA4D is a multifunctional target in many solid tumors, inv...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Yang, Lin, Liu, Xiaojun, Liu, Menghan, Liu, Jing, Feng, Xuefeng, Nie, Ziyuan, Luo, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258142/
https://www.ncbi.nlm.nih.gov/pubmed/35794581
http://dx.doi.org/10.1186/s12967-022-03500-w

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