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HDAC1 regulates inflammation and osteogenic differentiation of ankylosing spondylitis fibroblasts through the Wnt-Smad signaling pathway

Ankylosing spondylitis (AS) is a refractory autoimmune disease, whose typical pathology is the development of inflammation to ossification and ankylosis. Histone deacetylase 1 (HDAC1) is considered to be a key factor involved in inflammatory gene transduction, but its role in AS remains unclear. The...

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Detalles Bibliográficos
Autores principales: Zeng, Yong, He, Rui, Liu, Yong, Luo, Ting, Li, Qing, He, Yu, Fang, Miao, Wang, Taiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258155/
https://www.ncbi.nlm.nih.gov/pubmed/35794630
http://dx.doi.org/10.1186/s13018-022-03224-z