Rhein attenuates angiotensin II-induced cardiac remodeling by modulating AMPK–FGF23 signaling

BACKGROUND: Increasing evidence indicates that myocardial oxidative injury plays a crucial role in the pathophysiology of cardiac hypertrophy (CH) and heart failure (HF). The active component of rhubarb, rhein exerts significant actions on oxidative stress and inflammation. Nonetheless, its role in...

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Detalles Bibliográficos
Autores principales: Lu, Wei, Zhu, Hongqiao, Wu, Jiawen, Liao, Sheng, Cheng, Guobing, Li, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258170/
https://www.ncbi.nlm.nih.gov/pubmed/35794561
http://dx.doi.org/10.1186/s12967-022-03482-9

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