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Rhein attenuates angiotensin II-induced cardiac remodeling by modulating AMPK–FGF23 signaling
BACKGROUND: Increasing evidence indicates that myocardial oxidative injury plays a crucial role in the pathophysiology of cardiac hypertrophy (CH) and heart failure (HF). The active component of rhubarb, rhein exerts significant actions on oxidative stress and inflammation. Nonetheless, its role in...
Autores principales: | Lu, Wei, Zhu, Hongqiao, Wu, Jiawen, Liao, Sheng, Cheng, Guobing, Li, Xiaoyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258170/ https://www.ncbi.nlm.nih.gov/pubmed/35794561 http://dx.doi.org/10.1186/s12967-022-03482-9 |
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