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Molecular dissection of a hyper-aggressive CBFB-MYH11/FLT3-ITD–positive acute myeloid leukemia

Acute Myeloid Leukaemia (AML) is a haematological malignancy showing a hypervariable landscape of clinical outcomes and phenotypic differences, explainable by heterogeneity at the cellular and molecular level. Among the most common genomic alterations, CBFB-MYH11 rearrangement and FLT3-ITD gene muta...

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Detalles Bibliográficos
Autores principales: Lo Iudice, Gabriele, De Bellis, Eleonora, Savi, Arianna, Guarnera, Luca, Massacci, Alice, De Nicola, Francesca, Goeman, Frauke, Ottone, Tiziana, Divona, Mariadomenica, Pallocca, Matteo, Fanciulli, Maurizio, Voso, Maria Teresa, Ciliberto, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258203/
https://www.ncbi.nlm.nih.gov/pubmed/35794567
http://dx.doi.org/10.1186/s12967-022-03486-5