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The methyltransferase METTL3 promotes tumorigenesis via mediating HHLA2 mRNA m6A modification in human renal cell carcinoma

BACKGROUND: As an important N6-methyladenosine (m(6)A) regulator, abnormal expression of methyltransferase-like protein 3 (METTL3) has been reported in certain human cancers. Although some data have shown that METTL3 plays an essential role in the progression of clear-cell renal cell carcinoma RCC (...

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Detalles Bibliográficos
Autores principales:	Zhu, Dawei, Liu, Yingting, Chen, Junjun, Wang, Qi, Li, Yuan, Zhu, Yulan, Feng, Jun, Jiang, Jingting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258210/ https://www.ncbi.nlm.nih.gov/pubmed/35794583 http://dx.doi.org/10.1186/s12967-022-03496-3

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