Accelerated SARS-CoV-2 intrahost evolution leading to distinct genotypes during chronic infection

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The chronic infection hypothesis for novel SARS-CoV-2 variant emergence is increasingly gaining credence following the appearance of Omicron. Here we investigate intrahost evolution and genetic diversity of lineage B.1.517 during a SARS-CoV-2 chronic infection lasting for 471 days (and still ongoing...

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Detalles Bibliográficos
Autores principales: Chaguza, Chrispin, Hahn, Anne M., Petrone, Mary E., Zhou, Shuntai, Ferguson, David, Breban, Mallery I., Pham, Kien, Peña-Hernández, Mario A., Castaldi, Christopher, Hill, Verity, Schulz, Wade, Swanstrom, Ronald I., Roberts, Scott C., Grubaugh, Nathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258298/
https://www.ncbi.nlm.nih.gov/pubmed/35794895
http://dx.doi.org/10.1101/2022.06.29.22276868
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