Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery

Peptides constrained through multiple disulfides (or disulfide-rich peptides, DRPs) have been an emerging frontier for ligand and drug discovery. Such peptides have the potential to combine the binding capability of biologics with the stability and bioavailability of smaller molecules. However, DRPs...

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Detalles Bibliográficos
Autores principales: Wu, Yapei, Fan, Shihui, Dong, Meng, Li, Jinjing, Kong, Chuilian, Zhuang, Jie, Meng, Xiaoting, Lu, Shuaimin, Zhao, Yibing, Wu, Chuanliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258321/
https://www.ncbi.nlm.nih.gov/pubmed/35865895
http://dx.doi.org/10.1039/d2sc00924b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258321/
https://www.ncbi.nlm.nih.gov/pubmed/35865895
http://dx.doi.org/10.1039/d2sc00924b

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