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Structure-guided design of CPPC-paired disulfide-rich peptide libraries for ligand and drug discovery
Peptides constrained through multiple disulfides (or disulfide-rich peptides, DRPs) have been an emerging frontier for ligand and drug discovery. Such peptides have the potential to combine the binding capability of biologics with the stability and bioavailability of smaller molecules. However, DRPs...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258321/ https://www.ncbi.nlm.nih.gov/pubmed/35865895 http://dx.doi.org/10.1039/d2sc00924b |