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Striatal synaptic adaptations in Parkinson’s disease
The striatum is densely innervated by mesencephalic dopaminergic neurons that modulate acquisition and vigor of goal-directed actions and habits. This innervation is progressively lost in Parkinson’s disease (PD), contributing to the defining movement deficits of the disease. Although boosting dopam...
Autores principales: | Shen, Weixing, Zhai, Shenyu, Surmeier, D. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258525/ https://www.ncbi.nlm.nih.gov/pubmed/35272023 http://dx.doi.org/10.1016/j.nbd.2022.105686 |
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