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Genetic background and mistranslation frequency determine the impact of mistranslating tRNA(Ser)(UGG)

Transfer RNA variants increase the frequency of mistranslation, the misincorporation of an amino acid not specified by the “standard” genetic code, to frequencies approaching 10% in yeast and bacteria. Cells cope with these variants by having multiple copies of each tRNA isodecoder and through pathw...

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Detalles Bibliográficos
Autores principales:	Berg, Matthew D, Zhu, Yanrui, Loll-Krippleber, Raphaël, San Luis, Bryan-Joseph, Genereaux, Julie, Boone, Charles, Villén, Judit, Brown, Grant W, Brandl, Christopher J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Mutant Screen Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258585/ https://www.ncbi.nlm.nih.gov/pubmed/35587152 http://dx.doi.org/10.1093/g3journal/jkac125

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