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A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley
In the evolution of land plants, the plant immune system has experienced expansion in immune receptor and signaling pathways. Lineage-specific expansions have been observed in diverse gene families that are potentially involved in immunity but lack causal association. Here, we show that Rps8-mediate...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258809/ https://www.ncbi.nlm.nih.gov/pubmed/35857460 http://dx.doi.org/10.1126/sciadv.abn7258 |
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| author | Holden, Samuel Bergum, Molly Green, Phon Bettgenhaeuser, Jan Hernández-Pinzón, Inmaculada Thind, Anupriya Clare, Shaun Russell, James M. Hubbard, Amelia Taylor, Jodi Smoker, Matthew Gardiner, Matthew Civolani, Laura Cosenza, Francesco Rosignoli, Serena Strugala, Roxana Molnár, István Šimková, Hana Doležel, Jaroslav Schaffrath, Ulrich Barrett, Matthew Salvi, Silvio Moscou, Matthew J. |
| author_facet | Holden, Samuel Bergum, Molly Green, Phon Bettgenhaeuser, Jan Hernández-Pinzón, Inmaculada Thind, Anupriya Clare, Shaun Russell, James M. Hubbard, Amelia Taylor, Jodi Smoker, Matthew Gardiner, Matthew Civolani, Laura Cosenza, Francesco Rosignoli, Serena Strugala, Roxana Molnár, István Šimková, Hana Doležel, Jaroslav Schaffrath, Ulrich Barrett, Matthew Salvi, Silvio Moscou, Matthew J. |
| author_sort | Holden, Samuel |
| collection | PubMed |
| description | In the evolution of land plants, the plant immune system has experienced expansion in immune receptor and signaling pathways. Lineage-specific expansions have been observed in diverse gene families that are potentially involved in immunity but lack causal association. Here, we show that Rps8-mediated resistance in barley to the pathogen Puccinia striiformis f. sp. tritici (wheat stripe rust) is conferred by a genetic module: Pur1 and Exo70FX12, which are together necessary and sufficient. Pur1 encodes a leucine-rich repeat receptor kinase and is the ortholog of rice Xa21, and Exo70FX12 belongs to the Poales-specific Exo70FX clade. The Exo70FX clade emerged after the divergence of the Bromeliaceae and Poaceae and comprises from 2 to 75 members in sequenced grasses. These results demonstrate the requirement of a lineage-specific Exo70FX12 in Pur1-mediated immunity and suggest that the Exo70FX clade may have evolved a specialized role in receptor kinase signaling. |
| format | Online Article Text |
| id | pubmed-9258809 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | American Association for the Advancement of Science |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-92588092022-07-20 A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley Holden, Samuel Bergum, Molly Green, Phon Bettgenhaeuser, Jan Hernández-Pinzón, Inmaculada Thind, Anupriya Clare, Shaun Russell, James M. Hubbard, Amelia Taylor, Jodi Smoker, Matthew Gardiner, Matthew Civolani, Laura Cosenza, Francesco Rosignoli, Serena Strugala, Roxana Molnár, István Šimková, Hana Doležel, Jaroslav Schaffrath, Ulrich Barrett, Matthew Salvi, Silvio Moscou, Matthew J. Sci Adv Biomedicine and Life Sciences In the evolution of land plants, the plant immune system has experienced expansion in immune receptor and signaling pathways. Lineage-specific expansions have been observed in diverse gene families that are potentially involved in immunity but lack causal association. Here, we show that Rps8-mediated resistance in barley to the pathogen Puccinia striiformis f. sp. tritici (wheat stripe rust) is conferred by a genetic module: Pur1 and Exo70FX12, which are together necessary and sufficient. Pur1 encodes a leucine-rich repeat receptor kinase and is the ortholog of rice Xa21, and Exo70FX12 belongs to the Poales-specific Exo70FX clade. The Exo70FX clade emerged after the divergence of the Bromeliaceae and Poaceae and comprises from 2 to 75 members in sequenced grasses. These results demonstrate the requirement of a lineage-specific Exo70FX12 in Pur1-mediated immunity and suggest that the Exo70FX clade may have evolved a specialized role in receptor kinase signaling. American Association for the Advancement of Science 2022-07-06 /pmc/articles/PMC9258809/ /pubmed/35857460 http://dx.doi.org/10.1126/sciadv.abn7258 Text en Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Biomedicine and Life Sciences Holden, Samuel Bergum, Molly Green, Phon Bettgenhaeuser, Jan Hernández-Pinzón, Inmaculada Thind, Anupriya Clare, Shaun Russell, James M. Hubbard, Amelia Taylor, Jodi Smoker, Matthew Gardiner, Matthew Civolani, Laura Cosenza, Francesco Rosignoli, Serena Strugala, Roxana Molnár, István Šimková, Hana Doležel, Jaroslav Schaffrath, Ulrich Barrett, Matthew Salvi, Silvio Moscou, Matthew J. A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley |
| title | A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley |
| title_full | A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley |
| title_fullStr | A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley |
| title_full_unstemmed | A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley |
| title_short | A lineage-specific Exo70 is required for receptor kinase–mediated immunity in barley |
| title_sort | lineage-specific exo70 is required for receptor kinase–mediated immunity in barley |
| topic | Biomedicine and Life Sciences |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258809/ https://www.ncbi.nlm.nih.gov/pubmed/35857460 http://dx.doi.org/10.1126/sciadv.abn7258 |
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