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Oral doxycycline prevents skin-associated adverse effects induced by injectable collagenase in a rodent model of capsular contracture around silicone implants

BACKGROUND: The collagenase of the bacterium Clostridium histolyticum (CCH) is already an established treatment for fibroproliferative diseases like M. Dupuytren and M. Peyronie Although results are comparable to surgical intervention, skin laceration is a severe and relevant side effect. Doxycyclin...

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Detalles Bibliográficos
Autores principales:	Diehm, Yannick F., Kotsougiani-Fischer, Dimitra, Porst, Elena, Haug, Valentin, Siegwart, Laura C., Overhoff, Daniel, Kneser, Ulrich, Fischer, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258873/ https://www.ncbi.nlm.nih.gov/pubmed/35793344 http://dx.doi.org/10.1371/journal.pone.0270112

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