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Discovery of Quercetin and Its Analogs as Potent OXA-48 Beta-Lactamase Inhibitors

Carbapenem resistance in Enterobacteriaceae caused by OXA-48 β-lactamase is a growing global health threat and has rapidly spread in many regions of the world. Developing inhibitors is a promising way to overcome antibiotic resistance. However, there are few options for problematic OXA-48. Here we i...

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Detalles Bibliográficos
Autores principales: Zhang, Yuejuan, Chen, Cheng, Cheng, Bin, Gao, Lei, Qin, Chuan, Zhang, Lixia, Zhang, Xu, Wang, Jun, Wan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258905/
https://www.ncbi.nlm.nih.gov/pubmed/35814247
http://dx.doi.org/10.3389/fphar.2022.926104