What is the ideal management of Krukenberg syndrome?

We present the case of a 34-year-old female patient diagnosed with Krukenberg Syndrome, in which we performed total cytoreduction surgery of the lesions, with subsequent perioperative chemotherapy. After a follow-up of three years, we observe she continues without evidence of disease. In the early 1990’s Sugarbaker et al. introduced cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) as a new innovative therapy option for selected patients with peritoneal carcinomatosis. Nowadays, there is no established treatment for patients with peritoneal metastasis of colorectal cancer. There is a need for the future high-quality randomized multicenter trials to make a strong recommendation.