Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase

Translation is a tightly regulated process that ensures optimal protein quality and enables adaptation to energy/nutrient availability. The α-kinase eukaryotic elongation factor 2 kinase (eEF-2K), a key regulator of translation, specifically phosphorylates the guanosine triphosphatase eEF-2, thereby...

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Detalles Bibliográficos
Autores principales: Piserchio, Andrea, Isiorho, Eta A., Long, Kimberly, Bohanon, Amanda L., Kumar, Eric A., Will, Nathan, Jeruzalmi, David, Dalby, Kevin N., Ghose, Ranajeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258954/
https://www.ncbi.nlm.nih.gov/pubmed/35857468
http://dx.doi.org/10.1126/sciadv.abo2039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258954/
https://www.ncbi.nlm.nih.gov/pubmed/35857468
http://dx.doi.org/10.1126/sciadv.abo2039

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