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A Rare Case of Streptococcus Pneumoniae Causing Malignant Otitis Externa Complicated by Skull Base Osteomyelitis

Skull base osteomyelitis is an aggressive infection involving bones of the skull. It is a rare complication of malignant otitis externa, caused by the contiguous spread of the infection. Patients are mostly elderly with comorbidities that compromise immunity. It is atypical for Streptococcus species...

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Autores principales: Wahbah Makhoul, Gennifer, Mobarakai, Olivia, Manchandani, Umesh, Mobarakai, Neville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258965/
https://www.ncbi.nlm.nih.gov/pubmed/35812551
http://dx.doi.org/10.7759/cureus.25692
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author Wahbah Makhoul, Gennifer
Mobarakai, Olivia
Manchandani, Umesh
Mobarakai, Neville
author_facet Wahbah Makhoul, Gennifer
Mobarakai, Olivia
Manchandani, Umesh
Mobarakai, Neville
author_sort Wahbah Makhoul, Gennifer
collection PubMed
description Skull base osteomyelitis is an aggressive infection involving bones of the skull. It is a rare complication of malignant otitis externa, caused by the contiguous spread of the infection. Patients are mostly elderly with comorbidities that compromise immunity. It is atypical for Streptococcus species to be encountered in basilar skull osteomyelitis. Here we present the case of an 80-year-old male with multiple comorbidities including diabetes mellitus with a two-month history of right ear pain associated with occasional discharge and diminished hearing who was found to have bacteremia and basilar skull osteomyelitis with Streptococcus pneumoniae isolated from blood and otorrhea fluid cultures. This unusual presentation of S. pneumoniae related skull base osteomyelitis could be attributed to an undiagnosed pancreatic cancer at the time of presentation. Malignant otitis externa can progress into invasive disease in the head and neck; almost all cases tend to be caused by Pseudomonas aeruginosa but unusual cases, such as this, can be caused by Streptococcus pneumoniae.
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spelling pubmed-92589652022-07-08 A Rare Case of Streptococcus Pneumoniae Causing Malignant Otitis Externa Complicated by Skull Base Osteomyelitis Wahbah Makhoul, Gennifer Mobarakai, Olivia Manchandani, Umesh Mobarakai, Neville Cureus Internal Medicine Skull base osteomyelitis is an aggressive infection involving bones of the skull. It is a rare complication of malignant otitis externa, caused by the contiguous spread of the infection. Patients are mostly elderly with comorbidities that compromise immunity. It is atypical for Streptococcus species to be encountered in basilar skull osteomyelitis. Here we present the case of an 80-year-old male with multiple comorbidities including diabetes mellitus with a two-month history of right ear pain associated with occasional discharge and diminished hearing who was found to have bacteremia and basilar skull osteomyelitis with Streptococcus pneumoniae isolated from blood and otorrhea fluid cultures. This unusual presentation of S. pneumoniae related skull base osteomyelitis could be attributed to an undiagnosed pancreatic cancer at the time of presentation. Malignant otitis externa can progress into invasive disease in the head and neck; almost all cases tend to be caused by Pseudomonas aeruginosa but unusual cases, such as this, can be caused by Streptococcus pneumoniae. Cureus 2022-06-06 /pmc/articles/PMC9258965/ /pubmed/35812551 http://dx.doi.org/10.7759/cureus.25692 Text en Copyright © 2022, Wahbah Makhoul et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Wahbah Makhoul, Gennifer
Mobarakai, Olivia
Manchandani, Umesh
Mobarakai, Neville
A Rare Case of Streptococcus Pneumoniae Causing Malignant Otitis Externa Complicated by Skull Base Osteomyelitis
title A Rare Case of Streptococcus Pneumoniae Causing Malignant Otitis Externa Complicated by Skull Base Osteomyelitis
title_full A Rare Case of Streptococcus Pneumoniae Causing Malignant Otitis Externa Complicated by Skull Base Osteomyelitis
title_fullStr A Rare Case of Streptococcus Pneumoniae Causing Malignant Otitis Externa Complicated by Skull Base Osteomyelitis
title_full_unstemmed A Rare Case of Streptococcus Pneumoniae Causing Malignant Otitis Externa Complicated by Skull Base Osteomyelitis
title_short A Rare Case of Streptococcus Pneumoniae Causing Malignant Otitis Externa Complicated by Skull Base Osteomyelitis
title_sort rare case of streptococcus pneumoniae causing malignant otitis externa complicated by skull base osteomyelitis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9258965/
https://www.ncbi.nlm.nih.gov/pubmed/35812551
http://dx.doi.org/10.7759/cureus.25692
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