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A rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with COVID-19

INTRODUCTION: Coronavirus 2019 (COVID-19) can cause cardiovascular manifestations including myocardial injury and thromboembolic events. CASE PRESENTATION: Here, we report a case of a 27-year-old female with dilated cardiomyopathy, right atrial and biventricular thrombi infected with COVID-19. DISCU...

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Autores principales: Shah, Sangam, Yadav, Rukesh, Yadav, Sutap, Khanal, Rajaram, Poudel, Chandra Mani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259012/
https://www.ncbi.nlm.nih.gov/pubmed/35818400
http://dx.doi.org/10.1016/j.amsu.2022.104057
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author Shah, Sangam
Yadav, Rukesh
Yadav, Sutap
Khanal, Rajaram
Poudel, Chandra Mani
author_facet Shah, Sangam
Yadav, Rukesh
Yadav, Sutap
Khanal, Rajaram
Poudel, Chandra Mani
author_sort Shah, Sangam
collection PubMed
description INTRODUCTION: Coronavirus 2019 (COVID-19) can cause cardiovascular manifestations including myocardial injury and thromboembolic events. CASE PRESENTATION: Here, we report a case of a 27-year-old female with dilated cardiomyopathy, right atrial and biventricular thrombi infected with COVID-19. DISCUSSION: There are several complex coagulation abnormalities in COVID-19 patients that have been suggested to create a hypercoagulable state. Evidence have shown that endothelial injury potentially leading to thromboembolic events is caused by direct invasion of endothelial cell by SARS-CoV-2 and complement activation contributed by the virus spike protein. CONCLUSION: DCM can be complicated by atrial and biventricular thrombi due to coagulation abnormalities that are likely to persist after recovery from COVID-19. Thus, long-term careful monitoring of cardiac function is necessary after recovery of COVID-19.
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spelling pubmed-92590122022-07-07 A rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with COVID-19 Shah, Sangam Yadav, Rukesh Yadav, Sutap Khanal, Rajaram Poudel, Chandra Mani Ann Med Surg (Lond) Case Report INTRODUCTION: Coronavirus 2019 (COVID-19) can cause cardiovascular manifestations including myocardial injury and thromboembolic events. CASE PRESENTATION: Here, we report a case of a 27-year-old female with dilated cardiomyopathy, right atrial and biventricular thrombi infected with COVID-19. DISCUSSION: There are several complex coagulation abnormalities in COVID-19 patients that have been suggested to create a hypercoagulable state. Evidence have shown that endothelial injury potentially leading to thromboembolic events is caused by direct invasion of endothelial cell by SARS-CoV-2 and complement activation contributed by the virus spike protein. CONCLUSION: DCM can be complicated by atrial and biventricular thrombi due to coagulation abnormalities that are likely to persist after recovery from COVID-19. Thus, long-term careful monitoring of cardiac function is necessary after recovery of COVID-19. Elsevier 2022-07-06 /pmc/articles/PMC9259012/ /pubmed/35818400 http://dx.doi.org/10.1016/j.amsu.2022.104057 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shah, Sangam
Yadav, Rukesh
Yadav, Sutap
Khanal, Rajaram
Poudel, Chandra Mani
A rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with COVID-19
title A rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with COVID-19
title_full A rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with COVID-19
title_fullStr A rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with COVID-19
title_full_unstemmed A rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with COVID-19
title_short A rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with COVID-19
title_sort rare case of atrial and biventricular thrombi with dilated cardiomyopathy as a delayed presentation in a patient with covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259012/
https://www.ncbi.nlm.nih.gov/pubmed/35818400
http://dx.doi.org/10.1016/j.amsu.2022.104057
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