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The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

Natural killer (NK) cells are innate lymphocytes that eliminate virus-infected and cancer cells by cytotoxicity and cytokine secretion. In addition to circulating NK cells, distinct tissue-resident NK subsets have been identified in various organs. Although transcription factors regulating NK cell d...

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Detalles Bibliográficos
Autores principales:	Wahlen, Sigrid, Matthijssens, Filip, Van Loocke, Wouter, Taveirne, Sylvie, Kiekens, Laura, Persyn, Eva, Van Ammel, Els, De Vos, Zenzi, De Munter, Stijn, Matthys, Patrick, Van Nieuwerburgh, Filip, Taghon, Tom, Vandekerckhove, Bart, Van Vlierberghe, Pieter, Leclercq, Georges
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259014/ https://www.ncbi.nlm.nih.gov/pubmed/35793229 http://dx.doi.org/10.7554/eLife.80320

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