Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth

Cancer stem cells (CSCs) alone can initiate and maintain tumors, but the function of non-cancer stem cells (non-CSCs) that form the tumor bulk remains poorly understood. Proteomic analysis showed a higher abundance of the extracellular matrix small leucine-rich proteoglycan fibromodulin (FMOD) in th...

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Detalles Bibliográficos
Autores principales: Sengupta, Shreoshi, Mondal, Mainak, Prasasvi, Kaval Reddy, Mukherjee, Arani, Magod, Prerna, Urbach, Serge, Friedmann-Morvinski, Dinorah, Marin, Philippe, Somasundaram, Kumaravel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259034/
https://www.ncbi.nlm.nih.gov/pubmed/35642785
http://dx.doi.org/10.7554/eLife.78972

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