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Reconstitution of kinetochore motility and microtubule dynamics reveals a role for a kinesin-8 in establishing end-on attachments

During mitosis, individual microtubules make attachments to chromosomes via a specialized protein complex called the kinetochore to faithfully segregate the chromosomes to daughter cells. Translocation of kinetochores on the lateral surface of the microtubule has been proposed to contribute to high...

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Detalles Bibliográficos
Autores principales: Torvi, Julia R, Wong, Jonathan, Serwas, Daniel, Moayed, Amir, Drubin, David G, Barnes, Georjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259035/
https://www.ncbi.nlm.nih.gov/pubmed/35791811
http://dx.doi.org/10.7554/eLife.78450