Cargando…

Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814

New variants of the severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) emerged and spread rapidly all over the world, which strongly supports the need for pharmacological options to complement vaccine strategies. Main protease (M(pro) or 3CL(pro)) is a critical enzyme in the life cycle of...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jian, Lin, Cheng, Zhou, Xuelan, Zhong, Fanglin, Zeng, Pei, McCormick, Peter J., Jiang, Haihai, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259064/
https://www.ncbi.nlm.nih.gov/pubmed/35809383
http://dx.doi.org/10.1016/j.jmb.2022.167706