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Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children

In order to solve the stress problem in laparoscopic hiatal hernia repair of children, improve surgical safety, and reduce surgical risk, this study compared the perioperative changes of epinephrine, norepinephrine, IL-6, IL-10, and hemodynamics in children undergoing laparoscopic surgery under intr...

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Autores principales: Zhu, Xueli, Yang, Haiyang, Qu, Meimin, Wang, Jianshe, Fei, Jian, Shi, Linyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259264/
https://www.ncbi.nlm.nih.gov/pubmed/35845740
http://dx.doi.org/10.1155/2022/5290813
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author Zhu, Xueli
Yang, Haiyang
Qu, Meimin
Wang, Jianshe
Fei, Jian
Shi, Linyu
author_facet Zhu, Xueli
Yang, Haiyang
Qu, Meimin
Wang, Jianshe
Fei, Jian
Shi, Linyu
author_sort Zhu, Xueli
collection PubMed
description In order to solve the stress problem in laparoscopic hiatal hernia repair of children, improve surgical safety, and reduce surgical risk, this study compared the perioperative changes of epinephrine, norepinephrine, IL-6, IL-10, and hemodynamics in children undergoing laparoscopic surgery under intravenous general anesthesia and general anesthesia combined with an epidural block. In this study, 40 children aged 1–3 years who planned to undergo laparoscopic ortopexy and those who planned to undergo laparoscopic high ligation of hernia sac, aged 23.84 1.6 months and weighed 14.9 1.1 kg, were randomly divided into general anesthesia combined with the epidural block group (group A) and a total intravenous anesthesia group (group B), with 20 subjects in each group. The results are as follows: There were no differences in age, gender, body weight, anesthesia time, pneumoperitoneum duration, and functional time between the two groups. Cytokines: Compared with T0, the levels of IL-6 in T2, T3, T4, and T5 groups were significantly increased (P < 0.01). IL-10 levels: T2, T3, T4, and T5 groups were further increased, and the difference was statistically significant compared with T0 (P < 0.01). There was no difference between groups (P > 0.05). The recovery time in group B was shorter than that in group A (P < 0.01), and the total amount of propofol and fentanyl in group B was less than that in group A (P < 0.01). Through research on intravenous anesthesia treatment, it has been proved that total intravenous anesthesia can relieve perioperative pressure, reduce intravenous injection, and reduce the recovery time of children. However, its effect on cytokines is not obvious, so intravenous anesthesia is the most appropriate anesthesia mode in laparoscopic hiatal hernia repair surgery, which has practical significance.
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spelling pubmed-92592642022-07-14 Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children Zhu, Xueli Yang, Haiyang Qu, Meimin Wang, Jianshe Fei, Jian Shi, Linyu Contrast Media Mol Imaging Research Article In order to solve the stress problem in laparoscopic hiatal hernia repair of children, improve surgical safety, and reduce surgical risk, this study compared the perioperative changes of epinephrine, norepinephrine, IL-6, IL-10, and hemodynamics in children undergoing laparoscopic surgery under intravenous general anesthesia and general anesthesia combined with an epidural block. In this study, 40 children aged 1–3 years who planned to undergo laparoscopic ortopexy and those who planned to undergo laparoscopic high ligation of hernia sac, aged 23.84 1.6 months and weighed 14.9 1.1 kg, were randomly divided into general anesthesia combined with the epidural block group (group A) and a total intravenous anesthesia group (group B), with 20 subjects in each group. The results are as follows: There were no differences in age, gender, body weight, anesthesia time, pneumoperitoneum duration, and functional time between the two groups. Cytokines: Compared with T0, the levels of IL-6 in T2, T3, T4, and T5 groups were significantly increased (P < 0.01). IL-10 levels: T2, T3, T4, and T5 groups were further increased, and the difference was statistically significant compared with T0 (P < 0.01). There was no difference between groups (P > 0.05). The recovery time in group B was shorter than that in group A (P < 0.01), and the total amount of propofol and fentanyl in group B was less than that in group A (P < 0.01). Through research on intravenous anesthesia treatment, it has been proved that total intravenous anesthesia can relieve perioperative pressure, reduce intravenous injection, and reduce the recovery time of children. However, its effect on cytokines is not obvious, so intravenous anesthesia is the most appropriate anesthesia mode in laparoscopic hiatal hernia repair surgery, which has practical significance. Hindawi 2022-06-29 /pmc/articles/PMC9259264/ /pubmed/35845740 http://dx.doi.org/10.1155/2022/5290813 Text en Copyright © 2022 Xueli Zhu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhu, Xueli
Yang, Haiyang
Qu, Meimin
Wang, Jianshe
Fei, Jian
Shi, Linyu
Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children
title Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children
title_full Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children
title_fullStr Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children
title_full_unstemmed Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children
title_short Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children
title_sort application of intravenous anesthesia in laparoscopic hiatal hernia repair of children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259264/
https://www.ncbi.nlm.nih.gov/pubmed/35845740
http://dx.doi.org/10.1155/2022/5290813
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