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Trisomy 8-positive Polycythemia Vera Complicated with Intestinal Behçet's-like Disease: A New Perspective for a Clinical Approach
Behçet's disease (BD) is a multisystem inflammatory disease of unknown origin. It rarely but occasionally occurs together with myelodysplastic syndrome and primary myelofibrosis. Trisomy 8 is one of the most common cytogenetic abnormalities in myeloid neoplasms; however, the association of BD w...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japanese Society of Internal Medicine
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259299/ https://www.ncbi.nlm.nih.gov/pubmed/34744109 http://dx.doi.org/10.2169/internalmedicine.8395-21 |
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author | Mori, Yuki Iwamoto, Fumihiko Kuno, Toru Kobayashi, Shoji Yoshida, Takashi Yamaguchi, Tatsuya Takano, Shinichi Kondo, Tetsuo Kirito, Keita Enomoto, Nobuyuki |
author_facet | Mori, Yuki Iwamoto, Fumihiko Kuno, Toru Kobayashi, Shoji Yoshida, Takashi Yamaguchi, Tatsuya Takano, Shinichi Kondo, Tetsuo Kirito, Keita Enomoto, Nobuyuki |
author_sort | Mori, Yuki |
collection | PubMed |
description | Behçet's disease (BD) is a multisystem inflammatory disease of unknown origin. It rarely but occasionally occurs together with myelodysplastic syndrome and primary myelofibrosis. Trisomy 8 is one of the most common cytogenetic abnormalities in myeloid neoplasms; however, the association of BD with polycythemia vera (PV) and trisomy 8 has not been reported. A 70-year-old woman, diagnosed with PV and treated with hydroxyurea, had bloody stool due to multiple ulcers in the ileocecal region. Considering the lack of a response to treatment and other features, we suspected complication with intestinal Behçet's-like disease. Our case suggests relationships among BD, trisomy 8, and PV. |
format | Online Article Text |
id | pubmed-9259299 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-92592992022-07-19 Trisomy 8-positive Polycythemia Vera Complicated with Intestinal Behçet's-like Disease: A New Perspective for a Clinical Approach Mori, Yuki Iwamoto, Fumihiko Kuno, Toru Kobayashi, Shoji Yoshida, Takashi Yamaguchi, Tatsuya Takano, Shinichi Kondo, Tetsuo Kirito, Keita Enomoto, Nobuyuki Intern Med Case Report Behçet's disease (BD) is a multisystem inflammatory disease of unknown origin. It rarely but occasionally occurs together with myelodysplastic syndrome and primary myelofibrosis. Trisomy 8 is one of the most common cytogenetic abnormalities in myeloid neoplasms; however, the association of BD with polycythemia vera (PV) and trisomy 8 has not been reported. A 70-year-old woman, diagnosed with PV and treated with hydroxyurea, had bloody stool due to multiple ulcers in the ileocecal region. Considering the lack of a response to treatment and other features, we suspected complication with intestinal Behçet's-like disease. Our case suggests relationships among BD, trisomy 8, and PV. The Japanese Society of Internal Medicine 2021-11-06 2022-06-01 /pmc/articles/PMC9259299/ /pubmed/34744109 http://dx.doi.org/10.2169/internalmedicine.8395-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Mori, Yuki Iwamoto, Fumihiko Kuno, Toru Kobayashi, Shoji Yoshida, Takashi Yamaguchi, Tatsuya Takano, Shinichi Kondo, Tetsuo Kirito, Keita Enomoto, Nobuyuki Trisomy 8-positive Polycythemia Vera Complicated with Intestinal Behçet's-like Disease: A New Perspective for a Clinical Approach |
title | Trisomy 8-positive Polycythemia Vera Complicated with Intestinal Behçet's-like Disease: A New Perspective for a Clinical Approach |
title_full | Trisomy 8-positive Polycythemia Vera Complicated with Intestinal Behçet's-like Disease: A New Perspective for a Clinical Approach |
title_fullStr | Trisomy 8-positive Polycythemia Vera Complicated with Intestinal Behçet's-like Disease: A New Perspective for a Clinical Approach |
title_full_unstemmed | Trisomy 8-positive Polycythemia Vera Complicated with Intestinal Behçet's-like Disease: A New Perspective for a Clinical Approach |
title_short | Trisomy 8-positive Polycythemia Vera Complicated with Intestinal Behçet's-like Disease: A New Perspective for a Clinical Approach |
title_sort | trisomy 8-positive polycythemia vera complicated with intestinal behçet's-like disease: a new perspective for a clinical approach |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259299/ https://www.ncbi.nlm.nih.gov/pubmed/34744109 http://dx.doi.org/10.2169/internalmedicine.8395-21 |
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