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Polymyalgia Rheumatica Following COVID-19 Vaccination
We herein report a 71-year-old woman presented with a fever, arthralgia, general malaise and leg muscle stiffness following administration of the COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). Laboratory findings showed an elevated C-reactive protein level and erythrocyte sedimentation rate. In...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259323/ https://www.ncbi.nlm.nih.gov/pubmed/35342133 http://dx.doi.org/10.2169/internalmedicine.8934-21 |
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author | Yokote, Akira Fujioka, Shinsuke Takahashi, Nobutaka Mishima, Takayasu Tsuboi, Yoshio |
author_facet | Yokote, Akira Fujioka, Shinsuke Takahashi, Nobutaka Mishima, Takayasu Tsuboi, Yoshio |
author_sort | Yokote, Akira |
collection | PubMed |
description | We herein report a 71-year-old woman presented with a fever, arthralgia, general malaise and leg muscle stiffness following administration of the COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). Laboratory findings showed an elevated C-reactive protein level and erythrocyte sedimentation rate. In addition, Gallium-67 scintigraphy demonstrated an increased uptake in multiple joints. Typing of human leukocyte antigen (HLA) revealed the presence of the DRB1*0404/*0803 allele. These findings met the diagnostic criteria for polymyalgia rheumatica (PMR), and when we started steroid treatment, her symptoms improved rapidly. This patient developed PMR after receiving a COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). This case is considered to be valuable, as the HLA-DRB1 allele was also confirmed. |
format | Online Article Text |
id | pubmed-9259323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-92593232022-07-19 Polymyalgia Rheumatica Following COVID-19 Vaccination Yokote, Akira Fujioka, Shinsuke Takahashi, Nobutaka Mishima, Takayasu Tsuboi, Yoshio Intern Med Case Report We herein report a 71-year-old woman presented with a fever, arthralgia, general malaise and leg muscle stiffness following administration of the COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). Laboratory findings showed an elevated C-reactive protein level and erythrocyte sedimentation rate. In addition, Gallium-67 scintigraphy demonstrated an increased uptake in multiple joints. Typing of human leukocyte antigen (HLA) revealed the presence of the DRB1*0404/*0803 allele. These findings met the diagnostic criteria for polymyalgia rheumatica (PMR), and when we started steroid treatment, her symptoms improved rapidly. This patient developed PMR after receiving a COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). This case is considered to be valuable, as the HLA-DRB1 allele was also confirmed. The Japanese Society of Internal Medicine 2022-03-26 2022-06-01 /pmc/articles/PMC9259323/ /pubmed/35342133 http://dx.doi.org/10.2169/internalmedicine.8934-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Yokote, Akira Fujioka, Shinsuke Takahashi, Nobutaka Mishima, Takayasu Tsuboi, Yoshio Polymyalgia Rheumatica Following COVID-19 Vaccination |
title | Polymyalgia Rheumatica Following COVID-19 Vaccination |
title_full | Polymyalgia Rheumatica Following COVID-19 Vaccination |
title_fullStr | Polymyalgia Rheumatica Following COVID-19 Vaccination |
title_full_unstemmed | Polymyalgia Rheumatica Following COVID-19 Vaccination |
title_short | Polymyalgia Rheumatica Following COVID-19 Vaccination |
title_sort | polymyalgia rheumatica following covid-19 vaccination |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259323/ https://www.ncbi.nlm.nih.gov/pubmed/35342133 http://dx.doi.org/10.2169/internalmedicine.8934-21 |
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