KappaBle fluorescent reporter mice enable low-background single-cell detection of NF-κB transcriptional activity in vivo

Nuclear factor-κB (NF-κB) is a transcription factor with a key role in a great variety of cellular processes from embryonic development to immunity, the outcome of which depends on the fine-tuning of NF-κB activity. The development of sensitive and faithful reporter systems to accurately monitor the...

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Detalles Bibliográficos
Autores principales: Tortola, Luigi, Piattini, Federica, Hausmann, Annika, Ampenberger, Franziska, Rosenwald, Esther, Heer, Sebastian, Hardt, Wolf-Dietrich, Rülicke, Thomas, Kisielow, Jan, Kopf, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259492/
https://www.ncbi.nlm.nih.gov/pubmed/35589985
http://dx.doi.org/10.1038/s41385-022-00525-8

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