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HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine

Patients with mutations in HOIL1 experience a complex immune disorder including intestinal inflammation. To investigate the role of HOIL1 in regulating intestinal inflammation, we employed a mouse model of partial HOIL1 deficiency. The ileum of HOIL1-deficient mice displayed features of type 2 infla...

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Detalles Bibliográficos
Autores principales:	Wood, Matthew J., Marshall, Jeffrey N., Hartley, Victoria L., Liu, Ta-Chiang, Iwai, Kazuhiro, Stappenbeck, Thaddeus S., MacDuff, Donna A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259497/ https://www.ncbi.nlm.nih.gov/pubmed/35534698 http://dx.doi.org/10.1038/s41385-022-00520-z

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