Cargando…

Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies

Emergent application of antimicrobial strategies as symptomatic treatment in coronavirus disease (COVID-19) and linkage of severe acute respiratory syndrome coronavirus2 with microbial infections, has created colossal demand for antimicrobials. For the first time, this communication explore the phys...

Descripción completa

Detalles Bibliográficos
Autores principales: Pathania, Diksha, Kumar, Sunil, Thakur, Pankaj, Chaudhary, Vishal, Kaushik, Ajeet, Varma, Rajender S., Furukawa, Hidemitsu, Sharma, Mamta, Khosla, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259627/
https://www.ncbi.nlm.nih.gov/pubmed/35794190
http://dx.doi.org/10.1038/s41598-022-14984-3
_version_ 1784741827541204992
author Pathania, Diksha
Kumar, Sunil
Thakur, Pankaj
Chaudhary, Vishal
Kaushik, Ajeet
Varma, Rajender S.
Furukawa, Hidemitsu
Sharma, Mamta
Khosla, Ajit
author_facet Pathania, Diksha
Kumar, Sunil
Thakur, Pankaj
Chaudhary, Vishal
Kaushik, Ajeet
Varma, Rajender S.
Furukawa, Hidemitsu
Sharma, Mamta
Khosla, Ajit
author_sort Pathania, Diksha
collection PubMed
description Emergent application of antimicrobial strategies as symptomatic treatment in coronavirus disease (COVID-19) and linkage of severe acute respiratory syndrome coronavirus2 with microbial infections, has created colossal demand for antimicrobials. For the first time, this communication explore the physicochemical, antifungal, antibacterial, and photocatalytic properties of biogenic magnesium nanoparticles (MgNPs), synthesized using essential oil of Cymbopogon flexuosus's as an efficient multifunctional reducing and stabilizing/capping reagent. It is observed that MgNPs (ranging in size: 8–16 nm) of varying phytochemical compositions (MgS1, MgS2, MgS3) exhibited various useful physicochemical, antimicrobial, and photocatalytic properties. FTIR outcomes highlight the functional biomolecules-assisted reduction of Mg from Mg(+) to Mg(0). Among all, MgS3-Nps owing to the smallest particle size exhibited superior photocatalytic efficacy (91.2%) for the methylene blue degradation upon direct exposure to the sunlight for 3 h without using any reducing agents. Fabricated MgNPs also exhibited excellent antifungal (against Fusarium oxysporum) and antibacterial (versus Staphylococcus aureus and Escherichia coli) efficacies compared to state-of-the-art antimicrobial agents deployed for the treatment of infectious diseases. Based on this investigated greener approach, imperative from economic and environmental viewpoint, such essential oil based-MgNPs can be a potential nanosystem for various industrial applications where photocatalytic, and biomedical attributes are the key requirements.
format Online
Article
Text
id pubmed-9259627
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-92596272022-07-08 Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies Pathania, Diksha Kumar, Sunil Thakur, Pankaj Chaudhary, Vishal Kaushik, Ajeet Varma, Rajender S. Furukawa, Hidemitsu Sharma, Mamta Khosla, Ajit Sci Rep Article Emergent application of antimicrobial strategies as symptomatic treatment in coronavirus disease (COVID-19) and linkage of severe acute respiratory syndrome coronavirus2 with microbial infections, has created colossal demand for antimicrobials. For the first time, this communication explore the physicochemical, antifungal, antibacterial, and photocatalytic properties of biogenic magnesium nanoparticles (MgNPs), synthesized using essential oil of Cymbopogon flexuosus's as an efficient multifunctional reducing and stabilizing/capping reagent. It is observed that MgNPs (ranging in size: 8–16 nm) of varying phytochemical compositions (MgS1, MgS2, MgS3) exhibited various useful physicochemical, antimicrobial, and photocatalytic properties. FTIR outcomes highlight the functional biomolecules-assisted reduction of Mg from Mg(+) to Mg(0). Among all, MgS3-Nps owing to the smallest particle size exhibited superior photocatalytic efficacy (91.2%) for the methylene blue degradation upon direct exposure to the sunlight for 3 h without using any reducing agents. Fabricated MgNPs also exhibited excellent antifungal (against Fusarium oxysporum) and antibacterial (versus Staphylococcus aureus and Escherichia coli) efficacies compared to state-of-the-art antimicrobial agents deployed for the treatment of infectious diseases. Based on this investigated greener approach, imperative from economic and environmental viewpoint, such essential oil based-MgNPs can be a potential nanosystem for various industrial applications where photocatalytic, and biomedical attributes are the key requirements. Nature Publishing Group UK 2022-07-06 /pmc/articles/PMC9259627/ /pubmed/35794190 http://dx.doi.org/10.1038/s41598-022-14984-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Pathania, Diksha
Kumar, Sunil
Thakur, Pankaj
Chaudhary, Vishal
Kaushik, Ajeet
Varma, Rajender S.
Furukawa, Hidemitsu
Sharma, Mamta
Khosla, Ajit
Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies
title Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies
title_full Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies
title_fullStr Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies
title_full_unstemmed Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies
title_short Essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies
title_sort essential oil-mediated biocompatible magnesium nanoparticles with enhanced antibacterial, antifungal, and photocatalytic efficacies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259627/
https://www.ncbi.nlm.nih.gov/pubmed/35794190
http://dx.doi.org/10.1038/s41598-022-14984-3
work_keys_str_mv AT pathaniadiksha essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies
AT kumarsunil essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies
AT thakurpankaj essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies
AT chaudharyvishal essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies
AT kaushikajeet essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies
AT varmarajenders essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies
AT furukawahidemitsu essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies
AT sharmamamta essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies
AT khoslaajit essentialoilmediatedbiocompatiblemagnesiumnanoparticleswithenhancedantibacterialantifungalandphotocatalyticefficacies