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A novel mechanism for macrophage pyroptosis in rheumatoid arthritis induced by Pol β deficiency

Rheumatoid arthritis (RA) is a chronic and inflammatory autoimmune disease. Macrophage pyroptosis, a proinflammatory form of cell death, is critically important in RA; however, the detailed mechanism underlying pyroptosis induction is not yet well understood. Here, we report that DNA polymerase β (P...

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Detalles Bibliográficos
Autores principales:	Gu, Lili, Sun, Yuling, Wu, Ting, Chen, Ge, Tang, Xiaojun, Zhao, Lianfeng, He, Lingfeng, Hu, Zhigang, Sun, Lingyun, Pan, Feiyan, Yin, Zhimin, Guo, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259649/ https://www.ncbi.nlm.nih.gov/pubmed/35794098 http://dx.doi.org/10.1038/s41419-022-05047-6

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