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Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment

Toll-like receptors (TLRs) respond to pathogen constituents, such as microbial lipids and nucleic acids (NAs). TLRs recognize NAs in endosomal compartments. Structural and functional studies have shown that recognition of NAs by TLRs depends on NA processing by RNases and DNases. DNase II-dependent...

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Detalles Bibliográficos
Autores principales:	Miyake, Kensuke, Shibata, Takuma, Fukui, Ryutaro, Sato, Ryota, Saitoh, Shin-Ichiroh, Murakami, Yusuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259784/ https://www.ncbi.nlm.nih.gov/pubmed/35812450 http://dx.doi.org/10.3389/fimmu.2022.941931

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