Cargando…

Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019

BACKGROUND: Lead exposure is an important risk factor for stroke. However, the latest global spatiotemporal patterns of lead exposure-related stroke burden were unclear. In this study, we assessed this topic. METHODS: The data were obtained from the Global Burden of Disease Study (2019). The estimat...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Tongchao, Yin, Xiaolin, Zhang, Yuan, Chen, Hui, Man, Jinyu, Li, Yufei, Chen, Jiaqi, Yang, Xiaorong, Lu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259800/
https://www.ncbi.nlm.nih.gov/pubmed/35811690
http://dx.doi.org/10.3389/fcvm.2022.870747
_version_ 1784741864267579392
author Zhang, Tongchao
Yin, Xiaolin
Zhang, Yuan
Chen, Hui
Man, Jinyu
Li, Yufei
Chen, Jiaqi
Yang, Xiaorong
Lu, Ming
author_facet Zhang, Tongchao
Yin, Xiaolin
Zhang, Yuan
Chen, Hui
Man, Jinyu
Li, Yufei
Chen, Jiaqi
Yang, Xiaorong
Lu, Ming
author_sort Zhang, Tongchao
collection PubMed
description BACKGROUND: Lead exposure is an important risk factor for stroke. However, the latest global spatiotemporal patterns of lead exposure-related stroke burden were unclear. In this study, we assessed this topic. METHODS: The data were obtained from the Global Burden of Disease Study (2019). The estimated annual percentage change (EAPC) was estimated to evaluate the temporal trends of the age-standardized mortality and disability-adjusted life years (DALYs) rates (ASMR and ASDR) of stroke attributable to lead exposure. RESULTS: In 2019, the numbers of global stroke deaths and DALYs attributable to lead exposure were 305.27 and 6738.78 thousand, respectively. The corresponding ASMR and ASDR were highest in males, the elderly population, low and middle-income countries, and the intracerebral hemorrhage subtype. From 1990 to 2019, the ASMR and ASDR of global stroke attributable to lead exposure decreased [ASMR: EAPC = −1.34, 95% confidence interval (CI): (−1.57, −1.10); ASDR: EAPC = −1.74, 95% CI: (−1.95, −1.52)], especially in females, the high-income countries, and the subarachnoid hemorrhage subtype. CONCLUSION: This study emphasizes the importance of continued implementation of lead exposure prevention strategies and improved high-efficiency treatment and stroke acute health care, especially in low and middle-income countries.
format Online
Article
Text
id pubmed-9259800
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-92598002022-07-08 Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019 Zhang, Tongchao Yin, Xiaolin Zhang, Yuan Chen, Hui Man, Jinyu Li, Yufei Chen, Jiaqi Yang, Xiaorong Lu, Ming Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: Lead exposure is an important risk factor for stroke. However, the latest global spatiotemporal patterns of lead exposure-related stroke burden were unclear. In this study, we assessed this topic. METHODS: The data were obtained from the Global Burden of Disease Study (2019). The estimated annual percentage change (EAPC) was estimated to evaluate the temporal trends of the age-standardized mortality and disability-adjusted life years (DALYs) rates (ASMR and ASDR) of stroke attributable to lead exposure. RESULTS: In 2019, the numbers of global stroke deaths and DALYs attributable to lead exposure were 305.27 and 6738.78 thousand, respectively. The corresponding ASMR and ASDR were highest in males, the elderly population, low and middle-income countries, and the intracerebral hemorrhage subtype. From 1990 to 2019, the ASMR and ASDR of global stroke attributable to lead exposure decreased [ASMR: EAPC = −1.34, 95% confidence interval (CI): (−1.57, −1.10); ASDR: EAPC = −1.74, 95% CI: (−1.95, −1.52)], especially in females, the high-income countries, and the subarachnoid hemorrhage subtype. CONCLUSION: This study emphasizes the importance of continued implementation of lead exposure prevention strategies and improved high-efficiency treatment and stroke acute health care, especially in low and middle-income countries. Frontiers Media S.A. 2022-06-23 /pmc/articles/PMC9259800/ /pubmed/35811690 http://dx.doi.org/10.3389/fcvm.2022.870747 Text en Copyright © 2022 Zhang, Yin, Zhang, Chen, Man, Li, Chen, Yang and Lu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Zhang, Tongchao
Yin, Xiaolin
Zhang, Yuan
Chen, Hui
Man, Jinyu
Li, Yufei
Chen, Jiaqi
Yang, Xiaorong
Lu, Ming
Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019
title Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019
title_full Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019
title_fullStr Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019
title_full_unstemmed Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019
title_short Global Trends in Mortality and Burden of Stroke Attributable to Lead Exposure From 1990 to 2019
title_sort global trends in mortality and burden of stroke attributable to lead exposure from 1990 to 2019
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259800/
https://www.ncbi.nlm.nih.gov/pubmed/35811690
http://dx.doi.org/10.3389/fcvm.2022.870747
work_keys_str_mv AT zhangtongchao globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019
AT yinxiaolin globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019
AT zhangyuan globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019
AT chenhui globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019
AT manjinyu globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019
AT liyufei globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019
AT chenjiaqi globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019
AT yangxiaorong globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019
AT luming globaltrendsinmortalityandburdenofstrokeattributabletoleadexposurefrom1990to2019