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Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation
In general, the recipient's ABO blood type changes to the donor's ABO blood type after ABO-incompatible allogeneic hematopoietic stem cell transplantation (HSCT). However, we experienced a 26-year-old male with acute myelogenous leukemia (AML) who underwent ABO-incompatible HSCT twice and...
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japanese Society of Internal Medicine
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259807/ https://www.ncbi.nlm.nih.gov/pubmed/34803100 http://dx.doi.org/10.2169/internalmedicine.8315-21 |
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| author | Misaki, Yukiko Kako, Shinichi Kawamura, Shunto Takeshita, Junko Yoshino, Nozomu Yoshimura, Kazuki Gomyo, Ayumi Akahoshi, Yu Tamaki, Masaharu Kusuda, Machiko Kameda, Kazuaki Wada, Hidenori Kawamura, Koji Sato, Miki Terasako-Saito, Kiriko Kimura, Shun-ichi Nakasone, Hideki Kishino, Koji Muroi, Kazuo Kanda, Yoshinobu |
| author_facet | Misaki, Yukiko Kako, Shinichi Kawamura, Shunto Takeshita, Junko Yoshino, Nozomu Yoshimura, Kazuki Gomyo, Ayumi Akahoshi, Yu Tamaki, Masaharu Kusuda, Machiko Kameda, Kazuaki Wada, Hidenori Kawamura, Koji Sato, Miki Terasako-Saito, Kiriko Kimura, Shun-ichi Nakasone, Hideki Kishino, Koji Muroi, Kazuo Kanda, Yoshinobu |
| author_sort | Misaki, Yukiko |
| collection | PubMed |
| description | In general, the recipient's ABO blood type changes to the donor's ABO blood type after ABO-incompatible allogeneic hematopoietic stem cell transplantation (HSCT). However, we experienced a 26-year-old male with acute myelogenous leukemia (AML) who underwent ABO-incompatible HSCT twice and persistently showed his original blood type even after demonstrating complete donor-type chimerism. Based on the results of various examinations, we considered that the antigen of the recipient's original blood type persistently synthesized in the recipient's non-hematopoietic organs was secreted and adsorbed on the surface of donor-derived RBCs. We should therefore perform detailed examinations to determine the precise blood type after ABO-incompatible HSCT. |
| format | Online Article Text |
| id | pubmed-9259807 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | The Japanese Society of Internal Medicine |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-92598072022-07-19 Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation Misaki, Yukiko Kako, Shinichi Kawamura, Shunto Takeshita, Junko Yoshino, Nozomu Yoshimura, Kazuki Gomyo, Ayumi Akahoshi, Yu Tamaki, Masaharu Kusuda, Machiko Kameda, Kazuaki Wada, Hidenori Kawamura, Koji Sato, Miki Terasako-Saito, Kiriko Kimura, Shun-ichi Nakasone, Hideki Kishino, Koji Muroi, Kazuo Kanda, Yoshinobu Intern Med Case Report In general, the recipient's ABO blood type changes to the donor's ABO blood type after ABO-incompatible allogeneic hematopoietic stem cell transplantation (HSCT). However, we experienced a 26-year-old male with acute myelogenous leukemia (AML) who underwent ABO-incompatible HSCT twice and persistently showed his original blood type even after demonstrating complete donor-type chimerism. Based on the results of various examinations, we considered that the antigen of the recipient's original blood type persistently synthesized in the recipient's non-hematopoietic organs was secreted and adsorbed on the surface of donor-derived RBCs. We should therefore perform detailed examinations to determine the precise blood type after ABO-incompatible HSCT. The Japanese Society of Internal Medicine 2021-11-20 2022-06-15 /pmc/articles/PMC9259807/ /pubmed/34803100 http://dx.doi.org/10.2169/internalmedicine.8315-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Case Report Misaki, Yukiko Kako, Shinichi Kawamura, Shunto Takeshita, Junko Yoshino, Nozomu Yoshimura, Kazuki Gomyo, Ayumi Akahoshi, Yu Tamaki, Masaharu Kusuda, Machiko Kameda, Kazuaki Wada, Hidenori Kawamura, Koji Sato, Miki Terasako-Saito, Kiriko Kimura, Shun-ichi Nakasone, Hideki Kishino, Koji Muroi, Kazuo Kanda, Yoshinobu Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation |
| title | Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation |
| title_full | Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation |
| title_fullStr | Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation |
| title_full_unstemmed | Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation |
| title_short | Persistent Expression of Recipient-type ABH Antigen after ABO-incompatible Allogeneic Hematopoietic Stem Cell Transplantation |
| title_sort | persistent expression of recipient-type abh antigen after abo-incompatible allogeneic hematopoietic stem cell transplantation |
| topic | Case Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259807/ https://www.ncbi.nlm.nih.gov/pubmed/34803100 http://dx.doi.org/10.2169/internalmedicine.8315-21 |
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