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LncRNA MALAT1 Aggravates Renal Tubular Injury via Activating LIN28A and the Nox4/AMPK/mTOR Signaling Axis in Diabetic Nephropathy

BACKGROUND: Diabetic nephropathy (DN) is a serious complication among patients with diabetes. Elucidating its pathogenesis is crucial for identifying novel biomarkers and therapeutic targets for DN. METHODS: DN tissues were harvested for examining MALAT1, LIN28A and Nox4. Human kidney-2 (HK-2) cells...

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Detalles Bibliográficos
Autores principales: Song, Panai, Chen, Yinyin, Liu, Zhiwen, Liu, Hong, Xiao, Li, Sun, Lin, Wei, Jiali, He, Liyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259889/
https://www.ncbi.nlm.nih.gov/pubmed/35813614
http://dx.doi.org/10.3389/fendo.2022.895360