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Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients

While human immunodeficiency virus (HIV)-associated wasting has declined with significant advances in antiretroviral therapy (ART), weight gain and metabolic syndrome (MetS) are now becoming a problem for people living with HIV (PLWH) worldwide. The development of a new and more effective ART regime...

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Autor principal: Chang, Hyun-Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Infectious Diseases; Korean Society for Antimicrobial Therapy; The Korean Society for AIDS 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259920/
https://www.ncbi.nlm.nih.gov/pubmed/35706080
http://dx.doi.org/10.3947/ic.2022.0061
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author Chang, Hyun-Ha
author_facet Chang, Hyun-Ha
author_sort Chang, Hyun-Ha
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description While human immunodeficiency virus (HIV)-associated wasting has declined with significant advances in antiretroviral therapy (ART), weight gain and metabolic syndrome (MetS) are now becoming a problem for people living with HIV (PLWH) worldwide. The development of a new and more effective ART regimen has increased viral suppression and improved immunologic function recovery, leading to the extension of the lifespan of PLWH. It has recently been reported as one of the significant factors associated with weight gain, obesity, and long-term metabolic consequences in PLWH. This article reviewed the epidemiology of overweight and MetS among PLWH and the known risk factors for weight gain and its major comorbidities, such as dyslipidemia, diabetes mellitus, cardiovascular diseases, neurocognitive disorders, and liver diseases, in PLWH. In addition, reports on the pharmacological and surgical management of overweight and obesity in PLWH has been briefly summarized.
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spelling pubmed-92599202022-07-18 Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients Chang, Hyun-Ha Infect Chemother Review Article While human immunodeficiency virus (HIV)-associated wasting has declined with significant advances in antiretroviral therapy (ART), weight gain and metabolic syndrome (MetS) are now becoming a problem for people living with HIV (PLWH) worldwide. The development of a new and more effective ART regimen has increased viral suppression and improved immunologic function recovery, leading to the extension of the lifespan of PLWH. It has recently been reported as one of the significant factors associated with weight gain, obesity, and long-term metabolic consequences in PLWH. This article reviewed the epidemiology of overweight and MetS among PLWH and the known risk factors for weight gain and its major comorbidities, such as dyslipidemia, diabetes mellitus, cardiovascular diseases, neurocognitive disorders, and liver diseases, in PLWH. In addition, reports on the pharmacological and surgical management of overweight and obesity in PLWH has been briefly summarized. The Korean Society of Infectious Diseases; Korean Society for Antimicrobial Therapy; The Korean Society for AIDS 2022-06 2022-05-31 /pmc/articles/PMC9259920/ /pubmed/35706080 http://dx.doi.org/10.3947/ic.2022.0061 Text en Copyright © 2022 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Chang, Hyun-Ha
Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients
title Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients
title_full Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients
title_fullStr Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients
title_full_unstemmed Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients
title_short Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients
title_sort weight gain and metabolic syndrome in human immunodeficiency virus patients
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259920/
https://www.ncbi.nlm.nih.gov/pubmed/35706080
http://dx.doi.org/10.3947/ic.2022.0061
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