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Pressure Overload Activates DNA-Damage Response in Cardiac Stromal Cells: A Novel Mechanism Behind Heart Failure With Preserved Ejection Fraction?

Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome characterized by impaired left ventricular (LV) diastolic function, with normal LV ejection fraction. Aortic valve stenosis can cause an HFpEF-like syndrome by inducing sustained pressure overload (PO) and cardiac rem...

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Detalles Bibliográficos
Autores principales:	Stadiotti, Ilaria, Santoro, Rosaria, Scopece, Alessandro, Pirola, Sergio, Guarino, Anna, Polvani, Gianluca, Maione, Angela Serena, Ascione, Flora, Li, Qingsen, Delia, Domenico, Foiani, Marco, Pompilio, Giulio, Sommariva, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259931/ https://www.ncbi.nlm.nih.gov/pubmed/35811699 http://dx.doi.org/10.3389/fcvm.2022.878268

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