Functional divergence of the two Elongator subcomplexes during neurodevelopment

The highly conserved Elongator complex is a translational regulator that plays a critical role in neurodevelopment, neurological diseases, and brain tumors. Numerous clinically relevant variants have been reported in the catalytic Elp123 subcomplex, while no missense mutations in the accessory subco...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaik, Monika, Kojic, Marija, Stegeman, Megan R, Öncü‐Öner, Tülay, Kościelniak, Anna, Jones, Alun, Mohamed, Ahmed, Chau, Pak Yan Stefanie, Sharmin, Sazia, Chramiec‐Głąbik, Andrzej, Indyka, Paulina, Rawski, Michał, Biela, Anna, Dobosz, Dominika, Millar, Amanda, Chau, Vann, Ünalp, Aycan, Piper, Michael, Bellingham, Mark C, Eichler, Evan E, Nickerson, Deborah A, Güleryüz, Handan, Abbassi, Nour El Hana, Jazgar, Konrad, Davis, Melissa J, Mercimek‐Andrews, Saadet, Cingöz, Sultan, Wainwright, Brandon J, Glatt, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260213/
https://www.ncbi.nlm.nih.gov/pubmed/35698786
http://dx.doi.org/10.15252/emmm.202115608

Ejemplares similares

Ejemplares similares