Combined Systemic Intake of K-ATP Opener (Nicorandil) and Mesenchymal Stem Cells Preconditioned With Nicorandil Alleviates Pancreatic Insufficiency in a Model of Bilateral Renal Ischemia/Reperfusion Injury

We used nicorandil, a K-ATP channel opener, to study the role of these channels in the amelioration of renal ischemia/reperfusion (I/R)-induced pancreatic injury, and the possible involvement of PI3K/Akt/mTOR signaling pathway. Forty-two male Wistar rats were included in this study, six were sacrifi...

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Detalles Bibliográficos
Autores principales: ShamsEldeen, Asmaa Mohammed, El-Aal, Sarah A. Abd, Aboulhoda, Basma Emad, AbdAllah, Hend, Gamal, Sara Mahmoud, Hassan, Fatma E., Mehesen, Marwa Nagi, Rashed, Laila Ahmed, Mostafa, Abeer, Sadek, Nermeen Bakr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260271/
https://www.ncbi.nlm.nih.gov/pubmed/35812319
http://dx.doi.org/10.3389/fphys.2022.934597

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