Metabolic systems analysis identifies a novel mechanism contributing to shock in patients with endotheliopathy of trauma (EoT) involving thromboxane A2 and LTC(4)

PURPOSE: Endotheliopathy of trauma (EoT), as defined by circulating levels of syndecan-1 ≥ 40 ng/mL, has been reported to be associated with significantly increased transfusion requirements and a doubled 30-day mortality. Increased shedding of the glycocalyx points toward the endothelial cell membra...

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Detalles Bibliográficos
Autores principales: Henriksen, Hanne H., Marín de Mas, Igor, Herand, Helena, Krocker, Joseph, Wade, Charles E., Johansson, Pär I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles from the Special Issue on The Glycocalyx: Pathobiology and Repair; Edited by Jillian Richter & Ralph Sanderson
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260291/
https://www.ncbi.nlm.nih.gov/pubmed/35813244
http://dx.doi.org/10.1016/j.mbplus.2022.100115

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