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Accurate Identification of Subclones in Tumor Genomes

Understanding intratumor heterogeneity is critical for studying tumorigenesis and designing personalized treatments. To decompose the mixed cell population in a tumor, subclones are inferred computationally based on variant allele frequency (VAF) from bulk sequencing data. In this study, we showed t...

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Detalles Bibliográficos
Autores principales:	Ahmadinejad, Navid, Troftgruben, Shayna, Wang, Junwen, Chandrashekar, Pramod B, Dinu, Valentin, Maley, Carlo, Liu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260306/ https://www.ncbi.nlm.nih.gov/pubmed/35749590 http://dx.doi.org/10.1093/molbev/msac136

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