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PVT1 promotes resistance to 5-FU in colon cancer via the miR-486-5p/CDK4 axis

Drug resistance in tumors is a major issue, limiting the curative efficacy of currently available cancer chemotherapeutics. 5-Fluorouracil (5-FU) is a commonly applied therapeutic drug in colon cancer patient regimens; however, the majority of patients develop resistance to 5-FU in the later stages...

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Detalles Bibliográficos
Autores principales:	Luo, Zhuhe, Chen, Ruijun, Hu, Shen, Huang, Xibin, Huang, Zhenyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260730/ https://www.ncbi.nlm.nih.gov/pubmed/35814832 http://dx.doi.org/10.3892/ol.2022.13400

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