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Total Synthesis and Biological Evaluation of Clavatadines C–E

[Image: see text] We described herein the application of a convergent and protecting-group avoidant approach that led to the first total synthesis of the marine natural products clavatadine D (4) and E (5), and the second total synthesis of clavatadine C (3). In each case, a key amide-coupling affor...

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Detalles Bibliográficos
Autores principales:	Maxfield, Kylee, Payne, Morgan, Chamberland, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260760/ https://www.ncbi.nlm.nih.gov/pubmed/35811874 http://dx.doi.org/10.1021/acsomega.2c02913

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