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Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19
COVID-19 has been associated with cardiovascular events. This case demonstrates severe left main coronary artery thrombosis with distal embolisation in a young male patient admitted with COVID-19 who developed ST-elevation myocardial infarction. The patient was treated with thrombus aspiration combi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260788/ https://www.ncbi.nlm.nih.gov/pubmed/35793859 http://dx.doi.org/10.1136/bcr-2022-250011 |
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author | Johnsen, Jacob Kristensen, Steen Dalby Støttrup, Nicolaj Brejnholt |
author_facet | Johnsen, Jacob Kristensen, Steen Dalby Støttrup, Nicolaj Brejnholt |
author_sort | Johnsen, Jacob |
collection | PubMed |
description | COVID-19 has been associated with cardiovascular events. This case demonstrates severe left main coronary artery thrombosis with distal embolisation in a young male patient admitted with COVID-19 who developed ST-elevation myocardial infarction. The patient was treated with thrombus aspiration combined with aggressive anticoagulant treatment, which yielded complete resolution of the thrombus. Left main thrombus represents a life-threatening coronary event and is most often associated with atherosclerotic plaque rupture. In this case, however, we suspect that COVID-19-related intimal inflammation and hypercoagulopathy might be the causal mechanism of thrombus formation. Revascularisation with coronary artery bypass grafting or percutaneous coronary intervention is the standard treatment of left main thrombosis. However, due to the patient’s young age and lack of significant atherosclerotic disease burden, we used a conservative medical treatment strategy using potent antithrombotic therapy. |
format | Online Article Text |
id | pubmed-9260788 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-92607882022-07-25 Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19 Johnsen, Jacob Kristensen, Steen Dalby Støttrup, Nicolaj Brejnholt BMJ Case Rep Case Reports: Unusual presentation of more common disease/injury COVID-19 has been associated with cardiovascular events. This case demonstrates severe left main coronary artery thrombosis with distal embolisation in a young male patient admitted with COVID-19 who developed ST-elevation myocardial infarction. The patient was treated with thrombus aspiration combined with aggressive anticoagulant treatment, which yielded complete resolution of the thrombus. Left main thrombus represents a life-threatening coronary event and is most often associated with atherosclerotic plaque rupture. In this case, however, we suspect that COVID-19-related intimal inflammation and hypercoagulopathy might be the causal mechanism of thrombus formation. Revascularisation with coronary artery bypass grafting or percutaneous coronary intervention is the standard treatment of left main thrombosis. However, due to the patient’s young age and lack of significant atherosclerotic disease burden, we used a conservative medical treatment strategy using potent antithrombotic therapy. BMJ Publishing Group 2022-07-06 /pmc/articles/PMC9260788/ /pubmed/35793859 http://dx.doi.org/10.1136/bcr-2022-250011 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ. |
spellingShingle | Case Reports: Unusual presentation of more common disease/injury Johnsen, Jacob Kristensen, Steen Dalby Støttrup, Nicolaj Brejnholt Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19 |
title | Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19 |
title_full | Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19 |
title_fullStr | Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19 |
title_full_unstemmed | Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19 |
title_short | Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19 |
title_sort | minimally invasive treatment of left main coronary artery thrombosis in a young patient with covid-19 |
topic | Case Reports: Unusual presentation of more common disease/injury |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260788/ https://www.ncbi.nlm.nih.gov/pubmed/35793859 http://dx.doi.org/10.1136/bcr-2022-250011 |
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