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Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19

COVID-19 has been associated with cardiovascular events. This case demonstrates severe left main coronary artery thrombosis with distal embolisation in a young male patient admitted with COVID-19 who developed ST-elevation myocardial infarction. The patient was treated with thrombus aspiration combi...

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Autores principales: Johnsen, Jacob, Kristensen, Steen Dalby, Støttrup, Nicolaj Brejnholt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260788/
https://www.ncbi.nlm.nih.gov/pubmed/35793859
http://dx.doi.org/10.1136/bcr-2022-250011
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author Johnsen, Jacob
Kristensen, Steen Dalby
Støttrup, Nicolaj Brejnholt
author_facet Johnsen, Jacob
Kristensen, Steen Dalby
Støttrup, Nicolaj Brejnholt
author_sort Johnsen, Jacob
collection PubMed
description COVID-19 has been associated with cardiovascular events. This case demonstrates severe left main coronary artery thrombosis with distal embolisation in a young male patient admitted with COVID-19 who developed ST-elevation myocardial infarction. The patient was treated with thrombus aspiration combined with aggressive anticoagulant treatment, which yielded complete resolution of the thrombus. Left main thrombus represents a life-threatening coronary event and is most often associated with atherosclerotic plaque rupture. In this case, however, we suspect that COVID-19-related intimal inflammation and hypercoagulopathy might be the causal mechanism of thrombus formation. Revascularisation with coronary artery bypass grafting or percutaneous coronary intervention is the standard treatment of left main thrombosis. However, due to the patient’s young age and lack of significant atherosclerotic disease burden, we used a conservative medical treatment strategy using potent antithrombotic therapy.
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spelling pubmed-92607882022-07-25 Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19 Johnsen, Jacob Kristensen, Steen Dalby Støttrup, Nicolaj Brejnholt BMJ Case Rep Case Reports: Unusual presentation of more common disease/injury COVID-19 has been associated with cardiovascular events. This case demonstrates severe left main coronary artery thrombosis with distal embolisation in a young male patient admitted with COVID-19 who developed ST-elevation myocardial infarction. The patient was treated with thrombus aspiration combined with aggressive anticoagulant treatment, which yielded complete resolution of the thrombus. Left main thrombus represents a life-threatening coronary event and is most often associated with atherosclerotic plaque rupture. In this case, however, we suspect that COVID-19-related intimal inflammation and hypercoagulopathy might be the causal mechanism of thrombus formation. Revascularisation with coronary artery bypass grafting or percutaneous coronary intervention is the standard treatment of left main thrombosis. However, due to the patient’s young age and lack of significant atherosclerotic disease burden, we used a conservative medical treatment strategy using potent antithrombotic therapy. BMJ Publishing Group 2022-07-06 /pmc/articles/PMC9260788/ /pubmed/35793859 http://dx.doi.org/10.1136/bcr-2022-250011 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.
spellingShingle Case Reports: Unusual presentation of more common disease/injury
Johnsen, Jacob
Kristensen, Steen Dalby
Støttrup, Nicolaj Brejnholt
Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19
title Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19
title_full Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19
title_fullStr Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19
title_full_unstemmed Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19
title_short Minimally invasive treatment of left main coronary artery thrombosis in a young patient with COVID-19
title_sort minimally invasive treatment of left main coronary artery thrombosis in a young patient with covid-19
topic Case Reports: Unusual presentation of more common disease/injury
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260788/
https://www.ncbi.nlm.nih.gov/pubmed/35793859
http://dx.doi.org/10.1136/bcr-2022-250011
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