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Upregulation of SIRT1 by Evodiamine activates PI3K/AKT pathway and blocks intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is a major cause of a number of spinal diseases, resulting in serious public health problems. Evodiamine (Evo) is an indole quinazoline alkaloid extracted from Evodia rutaecarpa, which has antioxidant, anti-apoptosis and anti-inflammatory effects. The purpose o...

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Detalles Bibliográficos
Autores principales:	Kuai, Jianbo, Zhang, Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260874/ https://www.ncbi.nlm.nih.gov/pubmed/35762319 http://dx.doi.org/10.3892/mmr.2022.12781

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