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Practical Strategy to 1,1′-Dideoxygossypol Derivatives from Gossypol and Its Antitumor Activities

[Image: see text] A practical and scalable route for the synthesis of 1,1′-dideoxygossypol from natural polyphenol product gossypol is described. The key step is the successful regioselective deacetylation of hexaacetyl apogossypol 9 and the following reductive removal of hydroxyl groups. The two st...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Lu, Yuzhi, Ge, Juncheng, Liu, Niya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260933/
https://www.ncbi.nlm.nih.gov/pubmed/35811914
http://dx.doi.org/10.1021/acsomega.2c02955

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