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Molecular Mechanism of Protein Arginine Deiminase 2: A Study Involving Multiple Microsecond Long Molecular Dynamics Simulations

[Image: see text] Peptidylarginine deiminase 2 (PAD2) is a Ca(2+)-dependent enzyme that catalyzes the conversion of protein arginine residues to citrulline. This kind of structural modification in histone molecules may affect gene regulation, leading to effects that may trigger several diseases, inc...

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Detalles Bibliográficos
Autores principales:	Cicek, Erdem, Monard, Gerald, Sungur, Fethiye Aylin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260958/ https://www.ncbi.nlm.nih.gov/pubmed/35737372 http://dx.doi.org/10.1021/acs.biochem.2c00158

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