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In vitro Tau Aggregation Inducer Molecules Influence the Effects of MAPT Mutations on Aggregation Dynamics

[Image: see text] Alzheimer’s disease (AD) and Alzheimer’s disease-related dementias (ADRDs) affect 6 million Americans, and they are projected to have an estimated health care cost of $355 billion for 2021. A histopathological hallmark of AD and many ADRDs is the aberrant intracellular accumulation...

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Detalles Bibliográficos
Autores principales:	Ingham, David J., Hillyer, Kelsey M., McGuire, Madison J., Gamblin, Truman C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260964/ https://www.ncbi.nlm.nih.gov/pubmed/35731895 http://dx.doi.org/10.1021/acs.biochem.2c00111

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