A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants

BACKGROUND: With the continuous emergence of new SARS-CoV-2 variants that feature increased transmission and immune escape, there is an urgent demand for a better vaccine design that will provide broader neutralizing efficacy. METHODS: We report an mRNA-based vaccine using an engineered “hybrid” rec...

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Detalles Bibliográficos
Autores principales: Lee, I-Jung, Sun, Cheng-Pu, Wu, Ping-Yi, Lan, Yu-Hua, Wang, I-Hsuan, Liu, Wen-Chun, Yuan, Joyce Pei-Yi, Chang, Yu-Wei, Tseng, Sheng-Che, Tsung, Szu-I, Chou, Yu-Chi, Kumari, Monika, Lin, Yin-Shiou, Chen, Hui-Feng, Chen, Tsung-Yen, Lin, Chih-Chao, Chiu, Chi-Wen, Hsieh, Chung-Hsuan, Chuang, Cheng-Ying, Cheng, Chao-Min, Lin, Hsiu-Ting, Chen, Wan-Yu, Hsu, Fu-Fei, Hong, Ming-Hsiang, Liao, Chun-Che, Chang, Chih-Shin, Liang, Jian-Jong, Ma, Hsiu-Hua, Chiang, Ming-Tsai, Liao, Hsin-Ni, Ko, Hui-Ying, Chen, Liang-Yu, Ko, Yi-An, Yu, Pei-Yu, Yang, Tzu-Jing, Chiang, Po-Cheng, Hsu, Shang-Te, Lin, Yi-Ling, Lee, Chong-Chou, Wu, Han-Chung, Tao, Mi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261010/
https://www.ncbi.nlm.nih.gov/pubmed/35799178
http://dx.doi.org/10.1186/s12929-022-00830-1

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