Cargando…

Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis

Graphical representations of speech generate powerful computational measures related to psychosis. Previous studies have mostly relied on structural relations between words as the basis of graph formation, i.e., connecting each word to the next in a sequence of words. Here, we introduced a method of...

Descripción completa

Detalles Bibliográficos
Autores principales: Nikzad, Amir H., Cong, Yan, Berretta, Sarah, Hänsel, Katrin, Cho, Sunghye, Pradhan, Sameer, Behbehani, Leily, DeSouza, Danielle D., Liberman, Mark Y., Tang, Sunny X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261087/
https://www.ncbi.nlm.nih.gov/pubmed/35853912
http://dx.doi.org/10.1038/s41537-022-00263-7
_version_ 1784742196279246848
author Nikzad, Amir H.
Cong, Yan
Berretta, Sarah
Hänsel, Katrin
Cho, Sunghye
Pradhan, Sameer
Behbehani, Leily
DeSouza, Danielle D.
Liberman, Mark Y.
Tang, Sunny X.
author_facet Nikzad, Amir H.
Cong, Yan
Berretta, Sarah
Hänsel, Katrin
Cho, Sunghye
Pradhan, Sameer
Behbehani, Leily
DeSouza, Danielle D.
Liberman, Mark Y.
Tang, Sunny X.
author_sort Nikzad, Amir H.
collection PubMed
description Graphical representations of speech generate powerful computational measures related to psychosis. Previous studies have mostly relied on structural relations between words as the basis of graph formation, i.e., connecting each word to the next in a sequence of words. Here, we introduced a method of graph formation grounded in semantic relationships by identifying elements that act upon each other (action relation) and the contents of those actions (predication relation). Speech from picture descriptions and open-ended narrative tasks were collected from a cross-diagnostic group of healthy volunteers and people with psychotic or non-psychotic disorders. Recordings were transcribed and underwent automated language processing, including semantic role labeling to identify action and predication relations. Structural and semantic graph features were computed using static and dynamic (moving-window) techniques. Compared to structural graphs, semantic graphs were more strongly correlated with dimensional psychosis symptoms. Dynamic features also outperformed static features, and samples from picture descriptions yielded larger effect sizes than narrative responses for psychosis diagnoses and symptom dimensions. Overall, semantic graphs captured unique and clinically meaningful information about psychosis and related symptom dimensions. These features, particularly when derived from semi-structured tasks using dynamic measurement, are meaningful additions to the repertoire of computational linguistic methods in psychiatry.
format Online
Article
Text
id pubmed-9261087
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-92610872022-07-13 Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis Nikzad, Amir H. Cong, Yan Berretta, Sarah Hänsel, Katrin Cho, Sunghye Pradhan, Sameer Behbehani, Leily DeSouza, Danielle D. Liberman, Mark Y. Tang, Sunny X. Schizophrenia (Heidelb) Article Graphical representations of speech generate powerful computational measures related to psychosis. Previous studies have mostly relied on structural relations between words as the basis of graph formation, i.e., connecting each word to the next in a sequence of words. Here, we introduced a method of graph formation grounded in semantic relationships by identifying elements that act upon each other (action relation) and the contents of those actions (predication relation). Speech from picture descriptions and open-ended narrative tasks were collected from a cross-diagnostic group of healthy volunteers and people with psychotic or non-psychotic disorders. Recordings were transcribed and underwent automated language processing, including semantic role labeling to identify action and predication relations. Structural and semantic graph features were computed using static and dynamic (moving-window) techniques. Compared to structural graphs, semantic graphs were more strongly correlated with dimensional psychosis symptoms. Dynamic features also outperformed static features, and samples from picture descriptions yielded larger effect sizes than narrative responses for psychosis diagnoses and symptom dimensions. Overall, semantic graphs captured unique and clinically meaningful information about psychosis and related symptom dimensions. These features, particularly when derived from semi-structured tasks using dynamic measurement, are meaningful additions to the repertoire of computational linguistic methods in psychiatry. Nature Publishing Group UK 2022-07-05 /pmc/articles/PMC9261087/ /pubmed/35853912 http://dx.doi.org/10.1038/s41537-022-00263-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Nikzad, Amir H.
Cong, Yan
Berretta, Sarah
Hänsel, Katrin
Cho, Sunghye
Pradhan, Sameer
Behbehani, Leily
DeSouza, Danielle D.
Liberman, Mark Y.
Tang, Sunny X.
Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis
title Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis
title_full Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis
title_fullStr Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis
title_full_unstemmed Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis
title_short Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis
title_sort who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261087/
https://www.ncbi.nlm.nih.gov/pubmed/35853912
http://dx.doi.org/10.1038/s41537-022-00263-7
work_keys_str_mv AT nikzadamirh whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT congyan whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT berrettasarah whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT hanselkatrin whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT chosunghye whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT pradhansameer whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT behbehanileily whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT desouzadanielled whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT libermanmarky whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis
AT tangsunnyx whodoeswhattowhomgraphrepresentationsofactionpredicationinspeechrelatetopsychopathologicaldimensionsofpsychosis