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Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis
Graphical representations of speech generate powerful computational measures related to psychosis. Previous studies have mostly relied on structural relations between words as the basis of graph formation, i.e., connecting each word to the next in a sequence of words. Here, we introduced a method of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261087/ https://www.ncbi.nlm.nih.gov/pubmed/35853912 http://dx.doi.org/10.1038/s41537-022-00263-7 |
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author | Nikzad, Amir H. Cong, Yan Berretta, Sarah Hänsel, Katrin Cho, Sunghye Pradhan, Sameer Behbehani, Leily DeSouza, Danielle D. Liberman, Mark Y. Tang, Sunny X. |
author_facet | Nikzad, Amir H. Cong, Yan Berretta, Sarah Hänsel, Katrin Cho, Sunghye Pradhan, Sameer Behbehani, Leily DeSouza, Danielle D. Liberman, Mark Y. Tang, Sunny X. |
author_sort | Nikzad, Amir H. |
collection | PubMed |
description | Graphical representations of speech generate powerful computational measures related to psychosis. Previous studies have mostly relied on structural relations between words as the basis of graph formation, i.e., connecting each word to the next in a sequence of words. Here, we introduced a method of graph formation grounded in semantic relationships by identifying elements that act upon each other (action relation) and the contents of those actions (predication relation). Speech from picture descriptions and open-ended narrative tasks were collected from a cross-diagnostic group of healthy volunteers and people with psychotic or non-psychotic disorders. Recordings were transcribed and underwent automated language processing, including semantic role labeling to identify action and predication relations. Structural and semantic graph features were computed using static and dynamic (moving-window) techniques. Compared to structural graphs, semantic graphs were more strongly correlated with dimensional psychosis symptoms. Dynamic features also outperformed static features, and samples from picture descriptions yielded larger effect sizes than narrative responses for psychosis diagnoses and symptom dimensions. Overall, semantic graphs captured unique and clinically meaningful information about psychosis and related symptom dimensions. These features, particularly when derived from semi-structured tasks using dynamic measurement, are meaningful additions to the repertoire of computational linguistic methods in psychiatry. |
format | Online Article Text |
id | pubmed-9261087 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-92610872022-07-13 Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis Nikzad, Amir H. Cong, Yan Berretta, Sarah Hänsel, Katrin Cho, Sunghye Pradhan, Sameer Behbehani, Leily DeSouza, Danielle D. Liberman, Mark Y. Tang, Sunny X. Schizophrenia (Heidelb) Article Graphical representations of speech generate powerful computational measures related to psychosis. Previous studies have mostly relied on structural relations between words as the basis of graph formation, i.e., connecting each word to the next in a sequence of words. Here, we introduced a method of graph formation grounded in semantic relationships by identifying elements that act upon each other (action relation) and the contents of those actions (predication relation). Speech from picture descriptions and open-ended narrative tasks were collected from a cross-diagnostic group of healthy volunteers and people with psychotic or non-psychotic disorders. Recordings were transcribed and underwent automated language processing, including semantic role labeling to identify action and predication relations. Structural and semantic graph features were computed using static and dynamic (moving-window) techniques. Compared to structural graphs, semantic graphs were more strongly correlated with dimensional psychosis symptoms. Dynamic features also outperformed static features, and samples from picture descriptions yielded larger effect sizes than narrative responses for psychosis diagnoses and symptom dimensions. Overall, semantic graphs captured unique and clinically meaningful information about psychosis and related symptom dimensions. These features, particularly when derived from semi-structured tasks using dynamic measurement, are meaningful additions to the repertoire of computational linguistic methods in psychiatry. Nature Publishing Group UK 2022-07-05 /pmc/articles/PMC9261087/ /pubmed/35853912 http://dx.doi.org/10.1038/s41537-022-00263-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Nikzad, Amir H. Cong, Yan Berretta, Sarah Hänsel, Katrin Cho, Sunghye Pradhan, Sameer Behbehani, Leily DeSouza, Danielle D. Liberman, Mark Y. Tang, Sunny X. Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis |
title | Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis |
title_full | Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis |
title_fullStr | Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis |
title_full_unstemmed | Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis |
title_short | Who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis |
title_sort | who does what to whom? graph representations of action-predication in speech relate to psychopathological dimensions of psychosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261087/ https://www.ncbi.nlm.nih.gov/pubmed/35853912 http://dx.doi.org/10.1038/s41537-022-00263-7 |
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