Drosophila Lipase 3 Mediates the Metabolic Response to Starvation and Aging

The human LIPA gene encodes for the enzyme lysosomal acid lipase, which hydrolyzes cholesteryl ester and triacylglycerol. Lysosomal acid lipase deficiency results in Wolman disease and cholesteryl ester storage disease. The Drosophila genome encodes for two LIPA orthologs, Magro and Lipase 3. Magro...

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Detalles Bibliográficos
Autores principales: Hänschke, Lea, Heier, Christoph, Maya Palacios, Santiago José, Özek, Huseyin Erdem, Thiele, Christoph, Bauer, Reinhard, Kühnlein, Ronald P., Bülow, Margret H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261307/
https://www.ncbi.nlm.nih.gov/pubmed/35821816
http://dx.doi.org/10.3389/fragi.2022.800153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261307/
https://www.ncbi.nlm.nih.gov/pubmed/35821816
http://dx.doi.org/10.3389/fragi.2022.800153

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