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Drosophila Lipase 3 Mediates the Metabolic Response to Starvation and Aging
The human LIPA gene encodes for the enzyme lysosomal acid lipase, which hydrolyzes cholesteryl ester and triacylglycerol. Lysosomal acid lipase deficiency results in Wolman disease and cholesteryl ester storage disease. The Drosophila genome encodes for two LIPA orthologs, Magro and Lipase 3. Magro...
Autores principales: | Hänschke, Lea, Heier, Christoph, Maya Palacios, Santiago José, Özek, Huseyin Erdem, Thiele, Christoph, Bauer, Reinhard, Kühnlein, Ronald P., Bülow, Margret H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261307/ https://www.ncbi.nlm.nih.gov/pubmed/35821816 http://dx.doi.org/10.3389/fragi.2022.800153 |
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